Welcome To
Our research is focused on identifying genetic abnormalities in cancer cells, understanding how these changes influence the early development and progression of cancer, and discovering how this biology can inform selection of the best therapy for each patient.
We seek to discover actionable vulnerabilities of pre-cancerous and cancerous cells, and thereby uncover new approaches for prevention and treatment.
We explore basic cancer mechanisms, carry out high-throughput analysis of human tissues, and partner with computational biologists and clinical researchers in multi-disciplinary team-science.
our laboratory
We specialize in work at the interface between basic tumor biology and therapeutic application. We carry out detailed mechanistic studies, informed in part by state-of-the-art analysis of human normal and cancerous tissues. Our work is further enhanced through a network of collaborators at Harvard Medical School and MIT. We also benefit from the extraordinary research and clinical infrastructure of the MGH Cancer Center, providing us the opportunity to move key discoveries into clinical trials for the benefit of patients.